9.B.32 The DUF3302 or Pfam11742 (YibI) Family

The proteins of the DUF3302 family have two N-terminal TMSs followed by a ~50aa C-terminal hydrophilic region. The topology of YihI is established (Daley et al., 2005). These proteins have a well conserved GLPGR motif that may be involved in ATP/GTP binding or hydrolysis.


 

References:

Daley, D.O., M. Rapp, E. Granseth, K. Melén, D. Drew, and G. von Heijne. (2005). Global topology analysis of the Escherichia coli inner membrane proteome. Science 308: 1321-1323.

Zhu, N., S. Sun, F. Leng, W. Fan, J. Chen, J. Ma, H. He, G. Yang, and Y. Wang. (2022). Identification of Key Genes during Ca-Induced Genetic Transformation in by Combining Multi-Omics and Gene Knockout Techniques. Appl. Environ. Microbiol. 88: e0058722.

Examples:

TC#NameOrganismal TypeExample
9.B.32.1.1

DUF3302 (Pfam11742) protein; YibI (120aas, 2 TMSs; Daley et al., 2005).

Bacteria

YibI of E. coli (P32108)

 
9.B.32.1.2

YiaW of 107 aas and 2 central TMSs. Upon Ca2+ exposure for transformation of DNA plasmids, the level of this protein expressed increases and the amount of plasmid taken up also increases (Zhu et al. 2022).

Bacteria

YiaW of E. coli (P0ADK5)

 
9.B.32.1.3

Putative GTPase

Bacteria

Putative GTPase of Vibrio parahaemolyticus (B8K566)

 
9.B.32.1.4

DNA repair ATPase

Bacteria

ATPase of Aeromonas veronii (F4DGW5)

 
9.B.32.1.5

Hypothetical protein 

Bacteria

HP of Labrenzia alexandrii (B9QYG9)

 
9.B.32.1.6

Hypothetical protein (136aas; 2 TMSs)

Bacteria

HP of Ralstonia eutropha (Q0K0R7)

 
Examples:

TC#NameOrganismal TypeExample
9.B.32.2.1

Hypothetical protein (140aas; 2 TMSs) (has a GLPGR motif)

Bacteria

HP of Candidatus Accumulibacter phosphatis clade IIA (C7RSB7)