9.B.358. The DUF350 domain-containing (DUF350) Family This family consists of many integral membrane proteins of 250 to 300 aas with 8 TMSs in a 1 + 2 + 2 + 2 + 1 TMS arrangement, of 4 TMS proteins of half this size with a 1 + 2 + 1 TMS arrangement, and 2 TMS proteins of half this size. They derivse from a variety of bacteria and archaea. Their functions are unknown.
Examples:
TC#	Name	Organismal Type	Example
9.B.358.1.1	DUF350 domain-containing protein of 280 aas and 8 TMSs in a 1 + 2 + 2 + 2 + 1 TMS arrangement.		DUF350 protein of Desulfatibacillum aliphaticivorans

9.B.358.1.10	Uncharacterized DUF350 protein of 80 aas and 2 TMSs.		UP of Verrucomicrobia bacterium (freshwater metagenome)

9.B.358.1.11	Uncharacterized DUF350 protein of 68 aas and 2 TMSs		UP of Herpetosiphon

9.B.358.1.12	Uncharacterized DUF350 domain protein of 283 aas and 8 TMSs		UP of Sorangium cellulosum

9.B.358.1.2	Uncharacterized DUF350 domain protein of 64 aas and 2 TMSs, corresponding to TMSs 1 - 2 and 5 - 6 in the protein listed under TC# 9.B.358.1.1.		UP of Orenia marismortui

9.B.358.1.3	DUF350 domain-containing protein of 131 aas and 4 TMSs in a 1 + 2 + 1 TMS arrangement.		DUF350 protein of Planomicrobium koreense

9.B.358.1.4	DUF350 protein of 4 TMSs in a 1 + 2 + 1 TMS arrangement.		DUF350 protein of E. coli

9.B.358.1.5	Uncharacterized DUF350 protein of 161 aas and 4 TMSs in a 1 + 2 + 1 TMS arrangement.		UP of Methanophagales archaeon

9.B.358.1.6	Uncharacterized DUF350 protein of 334 aas with an N-terminal hydrophilic domain followed by a C-terminal 4 TMS hydrophobic domain.		UP of Aneurinibacillus aneurinilyticus

9.B.358.1.7	Uncharacterized DUF350 protein of 165 aas and 4 TMSs.		UP of Methanoregulaceae archaeon (sediment metagenome)

9.B.358.1.8	DUF350 protein of 145 aas and 4 TMSs		*UF350 protein of Streptomyces* sp. CB03234**

9.B.358.1.9	Uncharacterized DUF350 domain protein of 71 aas and 2 TMSs		UP of Flavobacterium circumlabens