9.B.361. The Small 4 TMS Protein (S4P) Family Most of the proteins of this family are of about 130 - 180 aas with 4 TMSs in a 3 + 1 TMS arrangement. However, some have only two TMSs corresponding to TMSs 1 & 2 or 3 & 4 of the 4 TMS proteins. 5 TMS homologues are also present in the family. Some members of this family have been annotated as 'hydrogenase'.
Examples:
TC#	Name	Organismal Type	Example
9.B.361.1.1	The Uncharacterized protein of 172 aas and 4 TMSs		UP of Calothrix elsteri

9.B.361.1.2	Uncharacterized protein of 152 aas and 4 TMSs.		UP of Serendipita vermifera (Sebacina vermifera)

Examples:
TC#	Name	Organismal Type	Example
9.B.361.2.1	Uncharacterized protein of 144 aas and 4 TMSs in a 3 + 1 TMS arrangement.		UP of Pseudoalteromonas rubra

9.B.361.2.2	Uncharacterized protein of 146 aas and 4 TMSs in a 3 + 1 TMS arrangement.		UP of Chrysiogenales bacterium (marine sediment metagenome)

9.B.361.2.3	Uncharacterized protein of 145 aas and 4 TMSs in a 3 + 1 TMS arrangement		UP of Mycolicibacter longobardus

Examples:
TC#	Name	Organismal Type	Example
9.B.361.3.1	Uncharacterized protein of 141 aas and 4 equally spaced TMSs		UP of Deltaproteobacteria bacterium (soil metagenome)

9.B.361.3.2	Uncharacterized protein of 141 aas and 4 TMSs.		UP of Candidatus Rokubacteria bacterium (soil metagenome)

9.B.361.3.3	Uncharacterized protein of 148 aas and 4 TMSs		UP of Zhongshania aliphaticivorans

Examples:
TC#	Name	Organismal Type	Example
9.B.361.4.1	Uncharacterized protein of 86 aas and 2 TMSs. This sequence is similar to TMSs 3 and 4 of a 4 TMS member and could be a fragment.		UP of Mycobacterium tuberculosis

9.B.361.4.2	Uncharacterized protein of 177 aas and 5 TMSs		UP of Polynucleobacter asymbioticus

9.B.361.4.3	Uncharacterized protein of 83 aas and 2 TMSs		*UP of Solemya velum* gill symbiont**

9.B.361.4.4	Uncharacterized protein of 93 aas and 2 TMSs, corresponding to TMSs 1 - 2 in the $ TMS proteins		*UP of Stanieria* sp.**