9.B.365.  The Putative 4 - 5 TMS DoxD (DoxD) superfamily

This family consists of small, 4 or 5 TMS proteins that are very diverse in sequence and belong to several distinct Pfam families.  At least some of these proteins are constituents of various dehydrogenases and oxidases.

 


Examples:

TC#NameOrganismal TypeExample
9.B.365.1.1

DoxD-like protein (FP07291, CL0131) MauE or TMEM101, methylamine utilization protein, of 257 aas and 5 TMSs in a 1 + 2 + 2 TMS arrangement.

MauE of Methylorubrum extorquens (Methylobacterium extorquens)

 
Examples:

TC#NameOrganismal TypeExample
9.B.365.2.1

RclC (PF04224, CL0131 DufD-like) of 215 aas and 5 TMSs in a 2 + 2 + 1 TMS arrangement.

RclC of Helicobacter pylori (Campylobacter pylori)

 
Examples:

TC#NameOrganismal TypeExample
9.B.365.3.1

DoxD-like protein (TMEM101; PF15111; CL0131) of 257 aas and 8 TMSs in a 1 + 2 + 2 + 2 + 1 TMS arrangement.

TMEM101 of Homo sapiens

 
Examples:

TC#NameOrganismal TypeExample
9.B.365.4.1

DoxD-like protein (PF13781; CL131), DoxX, NAD-dependent epimerase/dehydratase, of 430 aas and 4 C-terminal TMSs.

DoxX of Xanthobacter autotrophicus

 
Examples:

TC#NameOrganismal TypeExample
9.B.365.5.1

LMF1, DoxD-like protein (PF06762; CL131), Lipase maturation factor, of 644 aas and 11 TMSs in a 1 + 4 + 5 + 1 TMS arrangement.

LMF1 of Tetranychus urticae (Two-spotted spider mite)