9.B.379.  The Coronavirus Orf4b Membrane Protein (ORF4b) Family

The proteins of this family are of about 290 aas with 1 N-terminal TMS and possibly as many as 3 TMSs with low hydrophobicity.


TC#NameOrganismal TypeExample

Orf4b of 291 aas and 1 N-terminal TMS plus as many as 3 C-terminal TMSs with low levels of hydrophobicity.

Orf4b of Middle East Respiratory Syndrome-related Coronavirus


ORF4b of 884 aas with no N-terminal TMS, and maybe 3 non-hydrophobic central TMSs.

ORF4b of Tylonycteris bat coronavirus HKU4


Uncharacterized protein of 256 aas and possibly 3 low-hydrophobicity TMSs.

UP of Pipistrellus bat coronavirus HKU5