9.B.405.  The 7 TMS Uncharacterized Ubiquitous Protein-1 (UUP1) Family 

The proteins of this family are of about 240 aas and have 7 TMSs.  They occur in archaea, bacteria and eukaryotes. Members of the family have been annotated in the NCBI protein database as phytol kinases and phosphatidate cytidylyltransferases.


Examples:

TC#NameOrganismal TypeExample
9.B.405.1.1

Uncharacterized protein, possibly a phosphatidate cytidylyl transferase, of 241 aas and 7 TMSs in a 2 + 2 + 3 TMS arrangement.

UP of Candidatus Prometheoarchaeum syntrophicum

 
Examples:

TC#NameOrganismal TypeExample
9.B.405.2.1

Uncharacterized protein of 8 TMSs in an apparent 1 + 4 + 3 TMS arrangement.  Possibly it has a 4 TMS repeatsss and then would have a 1 + 3 + 1 + 3 TMS arrangement.

UP of Chloroflexi bacterium (marine sediment metagenome)

 
9.B.405.2.2

Phosphatidate cytidylyltransferase of 233 aas and 7 TMSs in a 1 + 1 + 2 + 3 TMS arrangement.

PCT of Calothrix parasitica

 
9.B.405.2.3

Cytidylyltransferase family protein of 227 aas and 5 or 6 TMSs in a 1 or 2 + 2 + 2 TMS arrangement.

CT protein of Spirochaetes bacterium ADurb.Bin110 (anaerobic digester metagenome)

 
Examples:

TC#NameOrganismal TypeExample
9.B.405.3.1

Phytol kinase of 241 aas and 8 TMSs in a 1 + 2 + 2 + 3 TMS arrangement.

Phytol kinase of Trifolium pratense

 
9.B.405.3.2

Uncharacterized protein of 580 aas and 15 TMSs in a 3 + 4 + 3 + 5 TMS arrangement.

UP of Diutina rugosa