9.B.426. The DUF4175/4401 (DUF4175/4401) Family This family consists of proteins that probably have 3 TMSs, sometimes with C-terminal hydrophilic domains, and sometimes with N-terminal hydrophilic domains. A few may have up to 6 TMSs, possiblly due to an internal duplication of the 3 TMS unit. These proteins may (or may not) be distantly related to protein 9.B.143.4.2 which may have 6 or 8 TMSs.
Examples:
TC#	Name	Organismal Type	Example
9.B.426.1.1	DUF4175 domain-containing protein of 243 aas and 3 TM		DUF4175 protein of Candidatus Kaiserbacteria bacterium (freshwater metagenome)

9.B.426.1.2	DUF4401 domain-containing protein of 288 aas and 3 TMSs.		DUF4401 protein of Candidatus Yonathbacteria bacterium (biofilm metagenome)

9.B.426.1.3	Uncharacterized protein of 177 aas and 3 TMSs.		UP of Candidatus Woesebacteria bacterium GW2011_GWD1_38_10 (groundwater metagenome)

9.B.426.1.4	Uncharacterized protein of 123 aas and 3 TMSs.		UP of Microgenomates group bacterium

9.B.426.1.5	Uncharacterized protein of 245 aas and 3 TMSs.		UP of Candidatus Berkelbacteria bacterium (groundwater metagenome)

9.B.426.1.6	Uncharacterized protein of 172 aas and 3 TMSs		UP of Candidatus Methanofastidiosa archaeon (anaerobic digester metagenome)

Examples:
TC#	Name	Organismal Type	Example
9.B.426.2.1	Uncharacterized protein of 293 aas with 3 C-terminal TMSs with an N-terminal hydrophilic domain.		UP of Saprospiraceae bacterium (activated sludge metagenome)

9.B.426.2.2	Uncharacterized protein of 253 aas and 3 N-terminal TMSs		*UP of Candidatus Parcubacteria bacterium (glacier metagenome) [Arenimonas* sp.]**

9.B.426.2.3	Uncharacterized protein of 271 aas and 3, 4, or 5 TMSs. This first 3 (N-terminal) hydrophobic peaks (TMSs) are large; the fourth is of moderate size, and the fifth is very small.		UP of Candidatus Wolfebacteria bacterium GW2011_GWB1_47_1 (groundwater metagenome)