9.B.444.  The Uncharacterized YjeO/YgiZ (YjeO/YgiZ) Family 

These two proteins (YjeO and YgiZ) are members of the YjeO family as well as the DUF2645 family.  They are small (~ 100 - 110 aa) proteins with 3 TMSs in a 1 + 2 TMS arrangement. The ygiZ gene is induced upon exposure of E. coli to external Ca2+ (Zhu et al. 2022).



Zhu, N., S. Sun, F. Leng, W. Fan, J. Chen, J. Ma, H. He, G. Yang, and Y. Wang. (2022). Identification of Key Genes during Ca-Induced Genetic Transformation in by Combining Multi-Omics and Gene Knockout Techniques. Appl. Environ. Microbiol. 88: e0058722.


TC#NameOrganismal TypeExample

YgiZ of 110 aas and 3 TMSs in a 1 + 2 TMS arrangement.  Its gene is induced by exposure to external Ca2+ used to induce transformation by plasmids (Zhu et al. 2022).

YgiZ of E. coli


YjeO inner membrane protein of 104 aas and 3 TMSs in a 1 + 3 TMS arrangement.

YjeO of E. coli


YgiZ of 108 aas and 3 TMSs in a 1 + 2 TMS arrangement.

YgiZ of Pectobacterium parmentieri


YjeO family protein of 112 aas and 3 TMSs.

YjeO of Serratia fonticola


Uncharacterized protein of 97 aas and 3 TMSs.

UP of Chania multitudinisentens