9.B.55 The 4 TMS DUF307/YccF (DUF307) Family This family includes the E. coli YccF 4 TMS protein of unknown function. This domain contains two 2 TMSs repeated in tandem. This 2 TMS domain is found in some calcium:cation antiporters of the CaCA family. These proteins have TC#s 2.A.19.7.1 &2.
Examples:
TC#	Name	Organismal Type	Example
9.B.55.1.1	The small 4 TMS protein, YccF of 148 aas and 4 putative TMSs.		YccF of E. coli

9.B.55.1.2	Uncharacterized DUF307 homologue of 131 aas and 4 TMS in a tandem 2 TMS repeated arrangement. Homologous to a 2 TMS N-terminal sequence in the CaCA family protein with TC# 2.A.19.7.1 & 2.		UP of Mycobacterium phlei (Mycobacterium smegmatis)

9.B.55.1.3	Uncharacterized protein of 193 aas and 4 TMSs.		*UP of Chlorella variabilis* (Green alga)**

Examples:
TC#	Name	Organismal Type	Example
9.B.55.2.1	Uncharacterized protein of 145 aas with two adjacent 2 TMS DUF307 domains.		UP of Perkinsus marinus

9.B.55.2.2	Uncharacterized protein of 313 aas with a C-terminal DUF375 domain of 4 putative TMSs, and a hydrophilic N-terminal domain with a long QPAG rich region of unknown function.		UP of Trichoplax adhaerens (Trichoplax reptans)