9.B.65 The Putative Transporter (YhgE) Family E. coli YhgE is a putative transporter of 574 aas with 11 putative TMSs and a C-terminal hydrophilic domain of nearly 200 residues. It belongs to the DUF4153 family. Homologues are of about 410-620 residues in length, and are from bacteria. None is functionally characterized. One of these proteins is 1825 aas long with 16 TMSs in a 4 + 4 + 4 + 4 TMS arrangement. Some members of this family are called pentapeptide repeat-containing proteins (PPRPs), but this motif is characteristic of a hydrophilic domain and seems not to be characteristic of all members of the family.
Examples:
TC#	Name	Organismal Type	Example
9.B.65.1.1	Putative transporter, YhgE	Proteobacteria	*YhgE of E. coli* (NP_417861)**

9.B.65.1.10	Uncharacterized protein of 410 aas and 11 TMSs.		UP of Sphaerochaeta globosa

9.B.65.1.2	Uncharacterized YhgE protein (DUF4153 family) of 592 aas and 11 TMSs.		UP of Desulfovibrio gigas

9.B.65.1.3	Uncharacterized YhgE homologue of the DUF4153 family; of 557 aas and 11 TMSs.		UP of Providencia stuartii

9.B.65.1.4	Uncharacterized protein of 596 aas and 12 TMSs.		UP of Phaeobacter inhibens (Phaeobacter gallaeciensis)

9.B.65.1.5	Uncharacterized protein of 373 aas and 12 TMSs.		UP of Legionella pneumophila

9.B.65.1.6	Uncharacterized protein of 456 aas and 11 TMSs		UP of Nitrolancea hollandica

9.B.65.1.7	Uncharacterized protein of 451 aas and 11 TMSs.		UP of Mycobacterium komanii

9.B.65.1.8	Uncharacterized protein of 607 aas and 11 TMSs.		UP of Candidatus Wirthbacteria bacterium

9.B.65.1.9	Uncharacterized protein of 537 aas and 11 N-terminal TMSs with a C-terminal pentapeptide repeat,		UP of Tatlockia micdadei