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|---|---|
| Accession Number: | Q9X4A5 |
| Protein Name: | Glycine betaine transporter BetL |
| Length: | 507 |
| Molecular Weight: | 55273.00 |
| Species: | Listeria monocytogenes [1639] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), glycine betaine |
Cross database links:
| Pfam: | PF02028 |
|---|---|
| KEGG: | lmo:lmo2092 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0015199
F:betaine transmembrane transporter activity
GO:0031460
P:glycine betaine transport
GO:0009409
P:response to cold
GO:0006970
P:response to osmotic stress
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References (4)[1] “Identification and disruption of BetL, a secondary glycine betaine transport system linked to the salt tolerance of Listeria monocytogenes LO28.” Sleator R.D.et.al. 10224004 [2] “Analysis of the role of betL in contributing to the growth and survival of Listeria monocytogenes LO28.” Sleator R.D.et.al. 11016615 [3] “Transcriptional regulation and posttranslational activity of the betaine transporter BetL in Listeria monocytogenes are controlled by environmental salinity.” Sleator R.D.et.al. 14645273 [4] “Molecular and physiological analysis of the role of osmolyte transporters BetL, Gbu, and OpuC in growth of Listeria monocytogenes at low temperatures.” Wemekamp-Kamphuis H.H.et.al. 15128551
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MKKLTNVFWG SGFLVLLAVL FGAFLPEQFE TFTNHIQKFL TSNFGWYYLI VVAIIIIFCL 61: FLVLSPIGSI RLGKPGEEPG YSNKSWFAML FSAGMGIGLV FWGAAEPLSH YAVQAPGGEV 121: GTQAAMKDAL RYSFFHWGIS AWSIYAIVAL ALAYFKFRKN APGLISATLY PILGKHAKGP 181: IGQLIDIIAV FATVIGVATT LGLGAQQING GLTYLFGVPN NFTVQFTIIV IVTILFMLSA 241: MSGLDKGIQL LSNVNIYVAG VLLVLTLILG PTLFIMNNFT NSFGDYLQNI IQMSFQTAPD 301: APDARKWIDS WTIFYWAWWL SWSPFVGIFI ARISRGRTIR QFLLGVIVLP ALVSVFWFAV 361: FGGSAIFVEQ HGNSGLSSLA TEQVLFGVFN EFPGGMMLSI VAMILIAVFF ITSADSATFV 421: LGMQTTGGSL NPPNSVKVTW GLLQAGIASV LLYAGGLTAL QNASIIAAFP FSIVIILMIV 481: SLFVSLTREQ EKLGLYVRPK KSQRSQL