TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.106.2.3
Golgi Ca2+:H+ and Mn2+:H+ antiporter, Gdt1 (GCR-1-dependent translation factor 1) or TMEM165 (Demaegd et al., 2013).  Involved in ion homeostasis (Dulary et al. 2016), specifically Mn2+ homeostasis (Thines et al. 2018).

Accession Number:P38301
Protein Name:GCR1-dependent translation factor 1
Length:280
Molecular Weight:30341.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate calcium(2+), proton, manganese(2+)

Cross database links:

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MGNMIKKASL IALLPLFTAA AAAATDAETS MESGSSSHLK SFLMSVSMIG LSEIGDKTFL 
61:	IAALMAMRHK RVLVFSAAAT SLAIMTILSG VVGHSAVAFL SERYTAFFAG ILFLVFGYKL 
121:	TMEGLEMSKD AGVEEEMAEV EEEIAIKDMN QDMDDVEKGG DTAYDKQLKN ASIGKKIVHR 
181:	IRELASFMFS PVWVQIFLMV FLGELGDRSQ ISIIAMATDS DYWYVIAGAV IGHAICSGLA 
241:	VVGGKLLATR ISIRTITLAS SLLFFIFALM YIYQAFTTQD