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2.A.3.2.6
Putative lysine uptake permease, YvsH (Rodionov et al., 2003)

Accession Number:O32204
Protein Name:YvsH
Length:469
Molecular Weight:50258.00
Species:Bacillus subtilis [1423]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate lysine

Cross database links:

HEGENOM: HBG586921
RefSeq: NP_391214.1   
Entrez Gene ID: 936000   
Pfam: PF00324   
BioCyc: SUBTI:BSU33330-MONOMER   
KEGG: bsu:BSU33330   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0015297 F:antiporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (2)

[1] “The yvsA-yvqA (293 degrees - 289 degrees) region of the Bacillus subtilis chromosome containing genes involved in metal ion uptake and a putative sigma factor.”  Wipat A.et.al.   9639930
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEQTKKWGFW LLTAFVVGNM VGSGIFSLPS SLASIASPFG ATSAWLLTGA GVLMIALVFG 
61:	HLSIRKPELT AGPQSYARAL FSDPKKGNAA GFTMVWGYWV ASWISNVAII TSLAGYLTSF 
121:	FPILVDKREM FSIGGQEVTL GQLLTFAVCT ILLWGTHAIL VASINGASKL NFVTTLSKVL 
181:	GFVFFIVAGL FVFQTSLFGH FYFPVQGENG TSIGIGGQVH NAAISTLWAF VGIESAVILS 
241:	GRARSQRDVK RATITGLLIA LSIYIIVTLI TMGVLPHDKL VGSEKPFVDV LYAIVGNAGS 
301:	VIMALLAILC LFGTMLGWIL LGSEVPYQAA KAGDFPAFFA KTNKKGSPVI ALIITNVMSQ 
361:	VFIFSVISRT ISDAFTFLTT AATLAYLIPY LVSAIYSLKV VIKGETYDQL KGSRVRDGLI 
421:	AILACAYSVF VIVTGTADLT TFILGIGLFF VGLIVYPFVS NKFQKEKQA