2.A.6.2.28
Multidrug efflux pump, AcrAB (Bina et al. 2008).
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| Accession Number: | A0Q8A5 |
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| Protein Name: | RND efflux transporter, AcrB/AcrD/AcrF family |
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| Length: | 1037 |
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| Molecular Weight: | 112512.00 |
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| Species: | Francisella tularensis subsp. novicida (strain U112) [401614] |
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| Number of TMSs: | 12 |
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| Substrate |
drug |
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1: MRLIDLFIRR PVLSLSISFM IIVVGVGSFF KLQVRQYPYI DSATITVTTS YPGANPATIQ
61: AFVTRPLEAA VGSSKGIDYM TSESALGTST ITVYVKLGYN TNDVLSEVVQ NVNSVLNQLP
121: QDAYSPAIKL NPADNFPSLI LAFTSKTMNT SEISAYINSE LTPKLLAEGG LSEINVWGNM
181: PYAMRIYPNK TRMAEYGITP TELATAIGSN SLVSAGGQIQ GPYLNYTLNP ETSMSTAQEY
241: RNLIIKKSDN QIVRLSDVAR VELGAQNYNS SVYFDGKNAV LAGAVVSPEE NPLDVVNRLV
301: KQLPNIKASL PNGLNVDVAY NSTLYIESSI DEVLHTLLEA VIIVSIVMFL FLGSLRAIIV
361: PIIAIPLSII GSFFLMSIMG FSINLLTLLA MILAIGLVVD DAIVVLENIY RHIEEGMEPF
421: AAAIKGAREI ANPVILMTLT LIVVYAPIGM MGGFTGQLFT EFAYSLAGAV LISGIVAYTL
481: SPMMCSKVLN REMMSSKLVK FIDNIFSKLA AKYKALLMFV LDIKPAIAIV GIIVLASCFI
541: MGKGIKSELA PNEDMGFLGV MGQAPSSANI NYLETFGKKL ANTLDEIPGK QNVFILNGVM
601: SSNVIFGGFI MQPWDERKIS QQQAANIAQA KVTELPGIQT YTYQTPALPG IPRGAPLSLV
661: IQSVNDYEAI DEITNKIIAK MMSSGLFVFA QSDLKFDNPI VDINIDRDKA GILGITMSDI
721: AKTLGYSYAG GYINYFFLKG YSFQVIPQLA RNEMLTQEQL GNIYIRSDEM NKLFDSEVPL
781: SALVTFKTEG QPLTLNTFQQ LNASTISAVM APGITQGQAI EYVQSVVKSM LPEGFSYNFS
841: GSARQYIENG NTMMVAFAFA IVLIFLALSA QFESFRDSLV ILVTIPMAIS GALIPLYVGQ
901: YLGASWASLN IYTQLGLVTL IGLISKQGIM VVEFANHLQK HNGMNKYDAI ITSSSQRLRP
961: ILMTVSAMVV GVIPLVTSSG AGAISRNCIG VVISSGLVIG AIFSLFVLPV VYMYIASDKS
1021: KSVKTDAEQQ QIIDQIK