3.A.2.1.7
F-type ATPase. The enzyme can synthesize but not hydrolyze ATP due to the presence of the zeta inhibitor. The crystal structure is known (Morales-Rios et al. 2015). The complex that was crystallized contains the nine core proteins of the complete F-ATPase complex plus the zeta
inhibitor protein. The formation of crystals depended upon the presence of bound bacterial
cardiolipin and phospholipid molecules; when they were removed, the complex failed to crystallize.
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| Accession Number: | A1B8N8 |
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| Protein Name: | ATP synthase subunit alpha |
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| Length: | 511 |
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| Molecular Weight: | 55039.00 |
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| Species: | Paracoccus denitrificans (strain Pd 1222) [318586] |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Peripheral membrane protein2 |
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| Substrate |
hydron |
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1: MGIQAAEISA ILKDQIKNFG QDAEVAEVGQ VLSVGDGIAR VYGLDKVQAG EMVEFPGGIR
61: GMVLNLETDN VGVVIFGDDR DIKEGDTVKR TGAIVEVPAG KELLGRVVDA LGNPIDGKGP
121: LNASERRIAD VKAPGIMPRK SVHEPMATGL KSVDAMIPVG RGQRELIIGD RQTGKTAIAL
181: DTILNQANYN GREADGMKTL HCIYVAVGQK RSTVAQLVKK LEETGAMAYT TVVAATASDP
241: APMQYLAPYS ATAMGEYFRD NGMDALIIYD DLSKQAVAYR QMSLLLRRPP GREAYPGDVF
301: YLHSRLLERS AKLNEANGAG SLTALPIIET QAGDVSAYIP TNVISITDGQ IFLETELFFQ
361: GIRPAVNTGL SVSRVGSAAQ TKAMKSVAGP VKLELAQYRE MAAFAQFGSD LDAATQKLLN
421: RGARLTELMK QPQYSPLTNA EIVIVIYAGT KGYLDGIPVR DVTKWEHGLL QYLRNQKADL
481: LEDMTKNDRK VAGELEDAIK AALDGYAKTY A