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3.A.6.1.1
Type III protein secretion complex. Assembly of the YscR,S,T,U,V complex occurs independently of other structural components and involves the formation of a YscV oligomer (Diepold et al., 2011). A C-terminal region of Yersinia pestis YscD binds the outer membrane secretin YscC (Ross and Plano, 2011). YopBD-mediated translocation of T3SS cargo, but not YopBD pore formation, leads to activation of host pathways influencing inflammation, cell death, and response to stress (Kwuan et al. 2013).

Accession Number:A1JU93
Protein Name:YscB
Length:137
Molecular Weight:15466.00
Species:Yersinia enterocolitica serotype O:8 / biotype 1B (strain 8081) [393305]
Location1 / Topology2 / Orientation3: Cytoplasm1 / Peripheral membrane protein2
Substrate protein polypeptide chain

Cross database links:

RefSeq: NP_783686.1    NP_863534.1    YP_001004089.1   
Entrez Gene ID: 1239210    1449478    4711849   
Pfam: PF05932   
KEGG: yen:YEP0037   

Gene Ontology

GO:0005737 C:cytoplasm
GO:0005886 C:plasma membrane
GO:0009405 P:pathogenesis
GO:0050708 P:regulation of protein secretion

References (2)

[1] “Complete DNA sequence of Yersinia enterocolitica serotype 0:8 low-calcium-response plasmid reveals a new virulence plasmid-associated replicon.”  Snellings N.J.et.al.   11402007
[2] “The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.”  Thomson N.R.et.al.   17173484

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MQNLLKNLAT SLGREPFVAD KQGVYRLTID KHLVMLAPHG SELVLRTPID APMLREGNNV 
61:	NVTLLRSLMQ QALAWAKRYP QTLVLDDCGQ LVLEARLRLQ ELDTHGLQEV INKQLALLEY 
121:	LIPQLTPFSV ASRVGWN