3.A.1.5.50
Peptide transporter, OppABCD of 591, 325, 291 and 612 aas with 1, 6, 6, and 0 TMSs, respectively. The high-resolution structures of Mycobacterium tuberculosis OppABCD in the
resting state, oligopeptide-bound pre-translocation state, AMPPNP-bound
pre-catalytic intermediate state and ATP-bound catalytic intermediate
state has been obtained. The structures show an assembly of a cluster C SBP with its ABC
translocator and a functionally required [4Fe-4S] cluster-binding domain
in OppD (Yang et al. 2024).
|
| Accession Number: | A5U1X9 |
|---|
| Protein Name: | Peptide ABC transporter ATP-binding protein |
|---|
| Length: | 612 |
|---|
| Molecular Weight: | 65293.00 |
|---|
| Species: | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [419947] |
|---|
| Substrate |
peptide |
|---|
1: MSPLLEVTDL AVTFRTDGDP VTAVRGISYR VEPGEVVAMV GESGSGKSAA AMAVVGLLPE
61: YAQVRGSVRL QGTELLGLAD NAMSRFRGKA IGTVFQDPMS ALTPVYTVGD QIAEAIEVHQ
121: PRVGKKAARR RAVELLDLVG ISQPQRRSRA FPHELSGGER QRVVIAIAIA NDPDLLICDE
181: PTTALDVTVQ AQILDVLKAA RDVTGAGVLI ITHDLGVVAE FADRALVMYA GRVVESAGVN
241: DLYRDRRMPY TVGLLGSVPR LDAAQGTRLV PIPGAPPSLA GLAPGCPFAP RCPLVIDECL
301: TAEPELLDVA TDHRAACIRT ELVTGRSAAD IYRVKTEARP AALGDASVVV RVRHLVKTYR
361: LAKGVVLRRA IGEVRAVDGI SLELRQGRTL GIVGESGSGK STTLHEILEL AAPQSGSIEV
421: LGTDVATLGT AERRSLRRDI QVVFQDPVAS LDPRLPVFDL IAEPLQANGF GKNETHARVA
481: ELLDIVGLRH GDASRYPAEF SGGQKQRIGI ARALALQPKI LALDEPVSAL DVSIQAGIIN
541: LLLDLQEQFG LSYLFVSHDL SVVKHLAHQV AVMLAGTVVE QGDSEEVFGN PKHEYTRRLL
601: GAVPQPDPAR RG