3.A.1.5.50
Peptide transporter, OppABCD of 591, 325, 291 and 612 aas with 1, 6, 6, and 0 TMSs, respectively. The high-resolution structures of Mycobacterium tuberculosis OppABCD in the
resting state, oligopeptide-bound pre-translocation state, AMPPNP-bound
pre-catalytic intermediate state and ATP-bound catalytic intermediate
state has been obtained. The structures show an assembly of a cluster C SBP with its ABC
translocator and a functionally required [4Fe-4S] cluster-binding domain
in OppD (Yang et al. 2024).
|
| Accession Number: | A5U1Y1 |
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| Protein Name: | Peptide ABC transporter permease protein |
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| Length: | 325 |
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| Molecular Weight: | 35083.00 |
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| Species: | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [419947] |
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| Number of TMSs: | 6 |
|---|
| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
peptide |
|---|
1: MTRYLARRLL NYLVLLALAS FLTYCLTSLA FSPLESLMQR SPRPPQAVID AKAHDLGLDR
61: PILARYANWV SHAVRGDFGT TITGQPVGTE LGRRIGVSLR LLVVGSVFGT VAGVVIGAWG
121: AIRQYRLSDR VMTTLALLVL STPTFVVANL LILGALRVNW AVGIQLFDYT GETSPGVAGG
181: VWDRLGDRLQ HLILPSLTLA LAAAAGFSRY QRNAMLDVLG QDFIRTARAK GLTRRRALLK
241: HGLRTALIPM ATLFAYGVAG LVTGAVFVEK IFGWHGMGEW MVRGISTQDT NIVAAITVFS
301: GAVVLLAGLL SDVIYAALDP RVRVS