TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.6.2.30
VexEF-TolC mediates resistance to various antimicrobials; ethidium efflux is Na+-dependent (Rahman et al., 2007)

Accession Number:A6P7H3
Protein Name:VexF
Length:1039
Molecular Weight:113991.00
Species:Vibrio cholerae [666]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ethidium, drug

Cross database links:

Pfam: PF00873   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Molecular Cloning and Characterization of All RND-Type Efflux Transporters in Vibrio cholerae Non-O1.”  Rahman M.M.et.al.   18037783

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MFTLIDAALS RTRTMLTLLV FILVAGVATY LTIPKESSPD VTIPIIYVSV THQGISPSDA 
61:	ERLIVRPLEQ EMRSIEGVKE MTATASEGHA SVVLEFNVGV DLAKAMADVR DAVDLAKPKL 
121:	PADSDEPTVN EVTLAAEQPV LSVVLYGTVP ERTAVLIARQ LRDKLESFRQ ILSVDIAGDR 
181:	EEIVEIIVDP LLMESYGLDQ SDIYNLIALN NRVVAAGFVD TGYGRFSVKV PSVFESLKDV 
241:	LELPIKVEGK QVITFGDVAT VRKSFRDPES FARLDGKPAI VLDIKKRSGE NIIETVELVK 
301:	AVLGEAQARD DWPNNLLVKT IWDESEDVKL MLNDLQNNIL SAIILVVVVI ITILGVRTSL 
361:	LVGVSIPGSF LTGLLVLAVF GLTVNIVVLF ALIMAVGMLV DGAIVVTEFA DRHMQEGMHR 
421:	SEAYRDAAKR MAWPITASTA TTLAAFAPLL FWPDVTGEFM KYLPLTLMAT LTASLVMALL 
481:	FVPVLGSLFG RPQKVTQANQ ARMVALHNGD FSQATGITKA YYHTLAIAIR HPIKILCGAL 
541:	LMSAAIAFAY GKAGLGAEFF PEVDPPFFSV KVRSYGDLSL NEKDRIMSDI EQVMLGHDEF 
601:	ESVYTRTGGG DEIGVVQITP VDWQYRRSVK AIIEELEQVT DTFPGVEIEY KFPDAGPPVE 
661:	HDLEIEISAR VADDLDKAAQ QVRLWAEANP ALTNLSDNGS KPGIDWKIDI RRDDASRFAA 
721:	DATLVGNTVQ FVTNGLKIGD YLPDDSDEEV DILVRYPSEY RDIGRFDQLR VKTAQGLVPL 
781:	TNFAQIIPEQ KQDTIHRVDG RRVISVMADL KEGYNLALEL PAIEQALREL NLPSSVEFRI 
841:	RGQNEEQEHS AVFLEKAFMV ALAAMAIILI TQFNSFYQSF LILTAVIFST VGVFAGLLIF 
901:	QKPFGIIMSG IGVIALAGIV VNNNIVLIDT YNQLLKRGLS REEAILRTGV QRLRPVLLTT 
961:	VTTILGLLPM VLEMNIDIIN QKIEFGAPST QWWSQLATAV AGGLAFATVL TLVLTPCLLM 
1021:	LGRRRKGVSE DEAPQDAQS