2.A.6.2.30
VexEF-TolC mediates resistance to various antimicrobials; ethidium efflux is Na+-dependent (Rahman et al., 2007)
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| Accession Number: | A6P7H3 |
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| Protein Name: | VexF |
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| Length: | 1039 |
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| Molecular Weight: | 113991.00 |
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| Species: | Vibrio cholerae [666] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
ethidium, drug |
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| Pfam: |
PF00873
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[1] “Molecular Cloning and Characterization of All RND-Type Efflux Transporters in Vibrio cholerae Non-O1.” Rahman M.M. et.al. 18037783
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1: MFTLIDAALS RTRTMLTLLV FILVAGVATY LTIPKESSPD VTIPIIYVSV THQGISPSDA
61: ERLIVRPLEQ EMRSIEGVKE MTATASEGHA SVVLEFNVGV DLAKAMADVR DAVDLAKPKL
121: PADSDEPTVN EVTLAAEQPV LSVVLYGTVP ERTAVLIARQ LRDKLESFRQ ILSVDIAGDR
181: EEIVEIIVDP LLMESYGLDQ SDIYNLIALN NRVVAAGFVD TGYGRFSVKV PSVFESLKDV
241: LELPIKVEGK QVITFGDVAT VRKSFRDPES FARLDGKPAI VLDIKKRSGE NIIETVELVK
301: AVLGEAQARD DWPNNLLVKT IWDESEDVKL MLNDLQNNIL SAIILVVVVI ITILGVRTSL
361: LVGVSIPGSF LTGLLVLAVF GLTVNIVVLF ALIMAVGMLV DGAIVVTEFA DRHMQEGMHR
421: SEAYRDAAKR MAWPITASTA TTLAAFAPLL FWPDVTGEFM KYLPLTLMAT LTASLVMALL
481: FVPVLGSLFG RPQKVTQANQ ARMVALHNGD FSQATGITKA YYHTLAIAIR HPIKILCGAL
541: LMSAAIAFAY GKAGLGAEFF PEVDPPFFSV KVRSYGDLSL NEKDRIMSDI EQVMLGHDEF
601: ESVYTRTGGG DEIGVVQITP VDWQYRRSVK AIIEELEQVT DTFPGVEIEY KFPDAGPPVE
661: HDLEIEISAR VADDLDKAAQ QVRLWAEANP ALTNLSDNGS KPGIDWKIDI RRDDASRFAA
721: DATLVGNTVQ FVTNGLKIGD YLPDDSDEEV DILVRYPSEY RDIGRFDQLR VKTAQGLVPL
781: TNFAQIIPEQ KQDTIHRVDG RRVISVMADL KEGYNLALEL PAIEQALREL NLPSSVEFRI
841: RGQNEEQEHS AVFLEKAFMV ALAAMAIILI TQFNSFYQSF LILTAVIFST VGVFAGLLIF
901: QKPFGIIMSG IGVIALAGIV VNNNIVLIDT YNQLLKRGLS REEAILRTGV QRLRPVLLTT
961: VTTILGLLPM VLEMNIDIIN QKIEFGAPST QWWSQLATAV AGGLAFATVL TLVLTPCLLM
1021: LGRRRKGVSE DEAPQDAQS