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2.A.6.3.14 BmeA5/B5/C5 multidrug efflux pump. BmeR5 is a local repressor of bmeABC5 expression, and mutations in the intergenic region between bmeR and bmeA led to derepression and resistance to multiple antimicrobial agents, including metronidazole (Pumbwe et al. 2007).
Accession Number:	AUI48178.1
Protein Name:	AUI48178.1 multidrug transporter AcrB [Bacteroides fragilis]
Length:	1053
Molecular Weight:
Species:	Bacteroides fragilis [817]
Number of TMSs:	12
Substrate	ciprofloxacin, ampicillin, cefoxitin, imipenem, ethidium bromide, sodium dodecyl sulfate, cefoperazone

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

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FASTA formatted sequence

1:	MSLYEGAVKK PIMTSLCFLA VVIFGLFSLS KLPIDLYPDI DTNTIMVMTA YPGASASDIE 
61:	NNVTRPLENT LNAVSNLKHI TSRSSENMSL ITLEFEYGND IDVLTNDVRD KLDMVSSQLP 
121:	DDVENPIIFK FSTDMIPIVL LSVQANESQS ALYKILDDRV VNPLARIPGV GTVSISGAPQ 
181:	REIQVYCDPN KLEAYNLTIE TISSIIGAEN KNIPGGNFDI GNETYSLRVE GEFDDSRQLE 
241:	DVVVGSYNGA NIYLRDVARV VDTVEERAQE TYNNGVKGAM IVVQKQSGAN SVDISKKVAE 
301:	ALPKLQKNLP SDVKLGVIVD TSDNILNTID SLAETVLYAL LFVVIVVFLF LGRWRATLII 
361:	CITIPLSLIA SFIYLAVTGN TINIISLSSL SIAIGMVVDD AIVVLENVTT HIERGSDPKQ 
421:	AAVHGTNEVA ISVIASTLTM IAVFFPLTMV SGMSGVMFKQ LGWMMCAIMF ISTVAALSLT 
481:	PMLCSQLLRL QKKQSKTFKL LFGPIEKGLD ALDTGYAHML NWAVRHRPIV IFGCIVFFVV 
541:	SLFCAKSIGT EFFPAQDNAR IAVQLELPIG TRKELAQEIS EKLTNQWLNK YKGVMTVCNY 
601:	TVGQADSDNT WASMQDNGSH IISFNISLVD PGDRDISLEQ VCDEMREDLK KYPEFSKAQV 
661:	ILGGSNTGMS AQASADFEVY GYSMEETDSV AARLKRELLN VKGVSEVNIS RSDYQPEYQV 
721:	DFDREKLALH GLNLATAGNY LRNRINGAIA SKYREDGDEY DIKVRYAPEH RTSIESIENI 
781:	LIYNSRGEAV RVKELGKVVE RFAPPTIERK DRERIVTVSA VISGEALGNV VNAGNAIIDK 
841:	MDIPSDVTIQ VAGSYEDQQD SFRDLGTLAI LIVVLVFIVM AAQFESLTYP FIIMFSLPFA 
901:	FSGVLMALFF TKSTLSVMSL LGAIMLIGIV VKNGIVLIDY ITLCRERGLA VLNSVVTAGK 
961:	SRLRPVLMTT ATTVLGMIPM AIGGGQGSEM WSPMAIAVIG GLTVSTILTL ILIPTLYCVF 
1021:	AGTGIKHQRK VLRRKRELEA YFEEHKDEMI KK

2.A.6.3.14
BmeA5/B5/C5 multidrug efflux pump. BmeR5 is a local repressor of bmeABC5 expression, and mutations in the intergenic region between bmeR and bmeA led to derepression and resistance to multiple antimicrobial agents, including metronidazole (Pumbwe et al. 2007).

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2.A.6.3.14BmeA5/B5/C5 multidrug efflux pump. BmeR5 is a local repressor of bmeABC5 expression, and mutations in the intergenic region between bmeR and bmeA led to derepression and resistance to multiple antimicrobial agents, including metronidazole (Pumbwe et al. 2007).

Cross database links:

External Searches:

Analyze:

2.A.6.3.14
BmeA5/B5/C5 multidrug efflux pump. BmeR5 is a local repressor of bmeABC5 expression, and mutations in the intergenic region between bmeR and bmeA led to derepression and resistance to multiple antimicrobial agents, including metronidazole (Pumbwe et al. 2007).