TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


4.A.6.1.13
Fucosyl-α-1,3-N-acetylglucosamine PTS uptake porter, AlfEFG (next to an operon encoding a fucosidase (AlfB) and a transcriptional regulator of the GntR family, AlfR).  The fucosidase is specific for this disaccharide which is present in mammalian glycoproteins, glycolipids and milk (Rodríguez-Díaz et al. 2012).  Uptake is dependent of AlfF but not on the PTS Enzyme I, suggesting that uptake does not require phosphorylation, consistent with the activity of AlfB as a fucosidase.  Only the glucosamine moiety is utilized and the fucose moiety, after hydrolysis, is excreted (Rodríguez-Díaz et al. 2012).

Accession Number:B3WB11
Protein Name:PTS system, IID component
Length:286
Molecular Weight:31418.00
Species:Lactobacillus casei (strain BL23) [543734]
Number of TMSs:6
Substrate Fucosyl-alpha-1,3-N-acetylglucosamine

Cross database links:

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MTIRIQTKEA MKMPSANTKT DLPVKLTKHD LFQANWRWLW GSQICWNYER MMSTGYLFTM 
61:	LPTLKKLYKN DQDLIEMMKM HNQFFNTNAY VGGFIVGMDM AIEEKQGRKA EDTVAGLKAG 
121:	LMGPFAGVGD TIVGVILPTI FGSIGAYMGL KGNPTGAILW LLVNFAVLIL RFFLLPLGYS 
181:	QGEKLIYATG DKLNRITDAA ILLGVTVVGA LIPTVISANV PLVFKTGKVV LKAQTVLDQI 
241:	MPSLVPVALV ALCYWLLGKK RMNSTRLIVL VLILGIALGA FGIIGK