3.A.1.27.7
Mce2A-F hetero-hexameric receptor complex of a lipid-transporting ABC uptake system. A Mycobacterium bovis Δmce2 double deletion mutant protects cattle against a challenge with virulent M. bovis (Blanco et al. 2013). The expression ratio of all selected mce operon genes in all M.
tuberculosis isolates was reduced at the initial phase and increased
substantially at a later phase of growth. Higher expression of mce1 operon genes was found in all M. tuberculosis isolates as compared to
other mce operon genes (mce2 and mce3 operons) at stationary growth
phase (Singh et al. 2016).
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| Accession Number: | I6Y461 |
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| Protein Name: | Possible Mce-family lipoprotein LprL (Mce-family lipoprotein Mce2E) |
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| Length: | 402 |
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| Molecular Weight: | 43174.00 |
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| Species: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332] |
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| Number of TMSs: | 1 |
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| Substrate |
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1: MRCGVSAGSA NGKPNRWTLR CGVSAGHRGS VFLLAVLLAP VVLTSCTWRG IANVPLPVGR
61: GMGPDRMTIY VQMPDTLALN TNSRVRVADV WVGTVRDISL RNWIATLTLE LEPTVRLPAN
121: ATAKIGQTSL LGTQHVELAA PPIPSPQPLK SGDTIGLKNS SAYPTVERTL ASVALILTGG
181: GIVNLDVIQT EILNILDGHA GQIREFLERL ATFTAELNNQ RGDLTRAIDS TNQLLTIIAN
241: RNDTLDRVLT DVPPLIEHFA DTGQLFADAT ESLGRFSEVA NRALAATRPN LHQTLQSLQR
301: PLRQLERASP YVVGALKLGL TAPFNIDEVP NVIRGDYVNV SATFDVTLSA LDNALLSGTG
361: ISGMLRALEQ AWGRDPDTMI PDVRYTPNPN DAPGGPLVER AE