3.A.1.134.5
The MDR exporter, YvcRS. Possibly linked to regulation by a sensor kinase/response regulator system (YvcQP) (Joseph et al., 2002; Bernard et al., 2007).
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| Accession Number: | O06981 |
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| Protein Name: | Uncharacterized ABC transporter permease yvcS |
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| Length: | 646 |
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| Molecular Weight: | 73398.00 |
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| Species: | Bacillus subtilis [1423] |
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| Number of TMSs: | 10 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
drug |
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| Entrez Gene ID: |
938473
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| Pfam: |
PF02687
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| KEGG: |
bsu:BSU34690
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[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F. et.al. 9384377
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1: MNLRTIARKN ILGNLQRYVA YFLSCVFAVS VFFVFTSFIF HPDVNEDNIY GGSLVKTCLS
61: AALVVIIVFC IFFITYSNSA FLQARKKEFG LLTLFGTSKQ QLRKMIYYEQ SLISLAAIAA
121: GIGAGLLFSK LFFMIMTWML SVKVPISFAI VPKAFVMTIA GFLILFQTLL ILSLGRIRKL
181: EIIELIKSAK KPKSLPVYSK WLTVLSLLCL GSGYYLSATA NAIDMMFRVF PILILVLIGT
241: YFFFTQSSVA FFRMLYRKKH SFYKGTNIIV RSNMIFRLKD HARMLFLTSV ITAVILTATG
301: VIYMFYSDLQ RQEEQSIPQS VSWVEKDASR FQVMKPETAE NTLKKAHAVI TYKVDATGIP
361: VTFQSDLPYG NKKMEAEALL ISEKVYNQVA KEKGFPVIHL QENEAFINVS FQMMVKDTFG
421: EGETAAFHMK SGKTLSYVMK KQQNKGILMS VDGVSRLLVV SEKSFDSLSQ DVPLKEQMRM
481: VGYELEHWQE TVDVSEKLEN MVPKEHTSDF QTRAPSYQIV KQGVALMLFI GLFVSVLFFI
541: VQGSMLYLRM FTEIEDTGVQ VLALKRIGVT DKEIHSILGK QIGFLFFIPF IAGTIHAGFA
601: YAALSNMLNS NLFLEAVIVI FIYFVFQALY YIVTRHIYKR AVLQRM