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3.A.1.12.4
Uptake system for choline, L-carnitine, D-carnitine, glycine betaine, proline betaine, crotonobetaine, γ-butyrobetaine, dimethylsulfonioacetate, dimethylsulfoniopropionate, ectoine and choline-O-sulfate

Accession Number:O34878
Protein Name:OPCB aka OpuCB
Length:217
Molecular Weight:23149.00
Species:Bacillus subtilis [1423]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate L-proline betaine, choline, glycine betaine, ectoine, carnitinium, (carboxymethyl)(dimethyl)sulfonium, (E)-4-(trimethylammonio)but-2-enoate, 4-(trimethylammonio)butanoate, S,S-dimethyl-beta-propiothetin

Cross database links:

RefSeq: NP_391262.1   
Entrez Gene ID: 937105   
Pfam: PF00528   
KEGG: bsu:BSU33820   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006865 P:amino acid transport

References (2)

[1] “Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.”  Kappes R.M.et.al.   10216873
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MNQMMTFLQT NGGELLYKTG EHLYISLIAV VLGIIVAVPL GVALTRMKKG AGAVIGFVNI 
61:	VQTLPSLAIL AFFIPLLGVG KVPAIVALFF YSVLPILRNT YTGIKGVNKN LLESGKGIGM 
121:	TGWEQIRLVE IPLAIPIIMA GIRTSTIYLI GWATLASFIG GGGLGDYIFI GLNLYQPEYI 
181:	IGGAVPVTIL AIIIDYVLAV TERKVTPKGL QGMKEVS