TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.114.1
Glycolipid exporter (under nitrogen control in heterocysts), DevABC-HgdD (Moslavac et al., 2007). Heterocyst envelope glycolipids (HGLs) function as an O2 diffusion barrier, being deposited over the heterocyst outer membrane, surrounded by an outermost heterocyst polysaccharide envelope. DevBCA and TolC form an ATP-driven efflux pump required for the export of HGLs across the Gram-negative cell wall (Staron et al., 2011). DevB, the MFP, must be hexameric to create a functional export complex.  This system is under NtcA and nitrogen control and is required for heterocyst development (Fiedler et al. 2001).

Accession Number:O50296
Protein Name:DevA
Length:244
Molecular Weight:26710.00
Species:Anabaena variabilis [1172]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate glycolipid

Cross database links:

RefSeq: YP_324089.1   
Entrez Gene ID: 3679358   
Pfam: PF00005   

Gene Ontology

GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity

References (1)

[1] “Sequence and mutational analysis of the devBCA gene cluster encoding a putative ABC transporter in the cyanobacterium Anabaena variabilis ATCC 29413.”  Fiedler G.et.al.   9767151

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MRQEAVIAIK SLNHYYGKGA LKRQILFDIN LEIYPGEIVI MTGPSGSGKT TLLSLIGGLR 
61:	SVQEGNLQFL GVELSGASQN KLVQIRRSIG YIFQAHNLLG FLTARQNVQM AVELNEHISQ 
121:	EEAIAKAEAM LKAVGLENRV DYYPDNLSGG QKQRVAIARA LVNNPPLVLA DEPTAALDKQ 
181:	SGRDVVEIMQ RLAKDQGTSI LLVTHDNRIL DIADRIVEME DGILARDSQT AIVSYDSGAW 
241:	SETP