3.A.1.2.28 Riboflavin uptake ABC transporter, RfuABCD. The periplasmic binding protein (RfuA) has been crystallized at 1.3 Å resolution with riboflavin bound (Deka et al. 2013). Similar systems are found in other spirochetes such as Treponema denticola, and Borrelia burgdorferi (Deka et al. 2013).
|
Accession Number: | O83323 |
Protein Name: | Conserved hypothetical integral membrane protein |
Length: | 377 |
Molecular Weight: | 40888.00 |
Species: | Treponema pallidum (strain Nichols) [243276] |
Number of TMSs: | 9 |
Substrate |
riboflavin |
---|
1: MKRVINSCIA VLLGVAVMSA VIVLCSENPS VSLAAFFLKP FSTRGYIRAL FHKAGLFVCM
61: ALGASCALKT GMINLGGDGQ IYAAGFVTAL LLREYWGVGF LLQWSVALLC ALSVAGILAC
121: VSGILKAWLA TSEMITSFLL STACVPLIDA LIITVTRDPA GNLLATAPVH SHFILQQQTS
181: LFGVPAVLTY ASLVALAVGC FFSYTRVGYQ FRICGKAPEF GRFVGFPVWA TYVWGMVLSG
241: ALFGLTGFFS VVGLFGTCYV GFSVGMGYAA LAHALIAHAH ITVLVPLAFF FAWMETASEA
301: AVLGAHLTVN VVLFLQAAIF LLISAQWSAP WNAVRRGARR VYRFLVTVFC FRGEKHRTRR
361: RHALSVHDTH HRRSRWE