3.A.1.14.28 Iron-siderophore (staphylobactin, made by S. aureus) uptake system, SirABCD (A = periplasmic receptor (R); B and C = membrane proteins with 9 or 10 TMSs (M), and D (IsdC) is likely to be the periplasmic auxiliary protein with 2 TMSs, N- and C-terminal (Dale et al. 2004). This last protein is also given the TC# 9.A.39.1.2 as a member of its own family. The ATPase subunit is not known, but it could be the protein with genbank acc# WP_001080807.1.
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Accession Number: | O87491 |
Protein Name: | Iron (Fe3+) ABC superfamily ATP binding cassette transporter, binding protein |
Length: | 330 |
Molecular Weight: | 36744.00 |
Species: | Staphylococcus aureus [1280] |
Number of TMSs: | 1 |
Substrate |
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1: MNKVIKMLVV TLAFLLVLAG CSGNSNKQSS DNKDKETTSI KHAMGTTEIK GKPKRVVTLY
61: QGATDVAVSL GVKPVGAVES WTQKPKFEYI KNDLKDTKIV GQEPAPNLEE ISKLKPDLIV
121: ASKVRNEKVY DQLSKIAPTV STDTVFKFKD TTKLMGKALG KEKEAEDLLK KYDDKVAAFQ
181: KDAKAKYKDA WPLKASVVNF RADHTRIYAG GYAGEILNDL GFKRNKDLQK QVDNGKDIIQ
241: LTSKESIPLM NADHIFVVKS DPNAKDAALV KKTESEWTSS KEWKNLDAVK NNQVSDDLDE
301: ITWNLAGGYK SSLKLIDDLY EKLNIEKQSK