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3.A.1.5.5 Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K⁺ homeostasis) [SapD can stimulate the K⁺ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)
Accession Number:	P0A2J3
Protein Name:	Peptide transport system permease protein SapB aka STM1693
Length:	321
Molecular Weight:	36111.00
Species:	Salmonella typhimurium [90371]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	cationic peptidyl group

RefSeq:	NP_460651.1
Entrez Gene ID:	1253211
Pfam:	PF00528
BioCyc:	STYP99287:STM1693-MONOMER
KEGG:	stm:STM1693
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0005215 F:transporter activity GO:0015833 P:peptide transport GO:0015031 P:protein transport
References (2) [1] “Molecular genetic analysis of a locus required for resistance to antimicrobial peptides in Salmonella typhimurium.” Parra-Lopez C.et.al. 8223423 [2] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.” McClelland M.et.al. 11677609

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MIIFTLRRLL LLLVTLFFLT FIGFSLSYFT PHAPLQGASL WNAWVFWFNG LLHWDFGVSS 
61:	INGQLISEQL KEVFPATMEL CILAFGFALM VGIPVGMLAG VTRSKWPDRF ISALALLGFS 
121:	IPVFWLALLL TLFFSLTLGW LPVSGRFDLL YEVKPVTGFA IIDAWISDSP WRDEMVMSAI 
181:	RHMVLPVLTL SVAPTTEVIR LMRISTIEVY DQNYVKAAAT RGLSRFTILR RHVLHNALPP 
241:	VIPRLGLQFS TMLTLAMITE MVFSWPGLGR WLIHAIRQQD YAAISAGVMV IGSLVIVVNV 
301:	ISDILGAMAN PLKHKEWYAL R

3.A.1.5.5
Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K⁺ homeostasis) [SapD can stimulate the K⁺ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)

Cross database links:

Gene Ontology

References (2)

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3.A.1.5.5Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K+ homeostasis) [SapD can stimulate the K+ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

3.A.1.5.5
Probable cationic peptide porter (may also take up peptide antibiotics and protamine; implicated in K⁺ homeostasis) [SapD can stimulate the K⁺ uptake activities of TrkH and TrkG (TC #2.A.38.1.1) in the presence of ATP] (Mason et al., 2006)