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3.A.1.15.6
Iron (Fe2+)/Zinc (Zn2+)/Copper (Cu2+) porter

Accession Number:P0A4G4
Protein Name:MtsA aka SPY0453
Length:310
Molecular Weight:34358.00
Species:Streptococcus pyogenes serotype [301447]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Lipid-anchor2
Substrate copper(2+), iron(2+), zinc(2+)

Cross database links:

RefSeq: NP_268747.1    YP_281731.1   
Entrez Gene ID: 3572540    900696   
Pfam: PF01297   
BioCyc: SPYO160490:SPY0453-MONOMER    SPYO293653:M5005_SPY0368-MONOMER   
KEGG: spy:SPy_0453    spz:M5005_Spy_0   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0046872 F:metal ion binding
GO:0007155 P:cell adhesion
GO:0006825 P:copper ion transport
GO:0006826 P:iron ion transport
GO:0006829 P:zinc ion transport

References (3)

[1] “Identification and characterization of a Streptococcus pyogenes ABC transporter with multiple specificity for metal cations.”  Janulczyk R.et.al.   10564500
[2] “Complete genome sequence of an M1 strain of Streptococcus pyogenes.”  Ferretti J.J.et.al.   11296296
[3] “Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events.”  Sumby P.et.al.   16088826
Structure:
3HH8     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MGKRMSLILG AFLSVFLLVA CSSTGTKTAK SDKLKVVATN SIIADMTKAI AGDKIDLHSI 
61:	VPIGQDPHEY EPLPEDVEKT SNADVIFYNG INLEDGGQAW FTKLVKNAQK TKNKDYFAVS 
121:	DGIDVIYLEG ASEKGKEDPH AWLNLENGII YSKNIAKQLI AKDPKNKETY EKNLKAYVAK 
181:	LEKLDKEAKS KFDAIAENKK LIVTSEGCFK YFSKAYGVPS AYIWEINTEE EGTPDQISSL 
241:	IEKLKVIKPS ALFVESSVDR RPMETVSKDS GIPIYSEIFT DSIAKKGKPG DSYYAMMKWN 
301:	LDKISEGLAK