2.A.79.2.1
YjjP (P0ADD5)/YjjB (P0ADD2) are of 256 aas and 5 TMSs; (DUF1212) and of 157 aas and 4 or 5 TMSs, respectively. yjjPB gene expression is regulated by HNS (a repressor) and LeuO (which antagonizes the repressive activity of HNS) (Stratmann et al. 2008). These proteins are encoded within a two gene operon, yjjPB, which encodes a two component dicarboxylate (succinate, fumarate and malate) transporter that has been shown to catalyze succinate efflux (Fukui et al. 2017). It is similar to the dicarboxylate/succinate transporter, YjjPB, of Enterobacter aerogenes (Fukui et al. 2018).
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| Accession Number: | P0ADD5 |
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| Protein Name: | Inner membrane protein YjjP |
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| Length: | 256 |
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| Molecular Weight: | 28001.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
fumarate(2-), malate(2-), succinate(2-) |
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1: MQTEQQRAVT RLCIQCGLFL LQHGAESALV DELSSRLGRA LGMDSVESSI SSNAIVLTTI
61: KDGQCLTSTR KNHDRGINMH VVTEVQHIVI LAEHHLLDYK GVEKRFSQIQ PLRYPRWLVA
121: LMVGLSCACF CKLNNGGWDG AVITFFASTT AMYIRQLLAQ RHLHPQINFC LTAFAATTIS
181: GLLLQLPTFS NTPTIAMAAS VLLLVPGFPL INAVADMFKG HINTGLARWA IASLLTLATC
241: VGVVMALTIW GLRGWV