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3.A.7.1.1
Conjugal DNA-protein transfer complexes. The VirB4 ATPase may mediate dislocation of the membrane-integrated VirB2 pilin (N- and C-termini out; cytoplasmic loop= residues 90-94 inside) during biogenesis of the Agrobacterium VirB/VirD4 type IV secretion system. VirB6 domains direct the ordered export of the DNA substrate through a type IV secretion System (Jakubowski et al. 2004).

Accession Number:P13464
Protein Name:VirD4
Length:671
Molecular Weight:73869.00
Species:Agrobacterium rhizogenes [359]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate protein polypeptide chain

Cross database links:

Pfam: PF02534   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0009291 P:unidirectional conjugation

References (1)

[1] “Organization and characterization of the virCD genes from Agrobacterium rhizogenes.”  Hirayama T.et.al.   3185501

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MNSSKITPQR LALSIVCSLA AGFCAASLYA TFRHGFNGEA MMTFSVFAFW YETPLYIGHA 
61:	TPVFFCGLSI IIATSVVVLL SQLIISLRNR EHHGTARWAA FGEMRHAGYL QRYNRIKGPV 
121:	FGKTCGPLWF GNYLTNGEQP HSLVVAPTRA GKGVGVVIPT LLTFKGTVIA LDVKGELFEL 
181:	TSRARKSSGD AVFKFSPLDP ERRTHCYNPV LDIAALPPER QFTETRRLAA NLITAKGKGA 
241:	EGFIDGARDL FVAGILTCIE RGTPTIGAVY DLFAQPGEKY KLFAHLAEES RNKEAQRIFD 
301:	NMAGNDTKIL TSYTSVLGDG GLNLWADPLV KAATSRSDFS VYDLRRKRTC VYLCVSPNDL 
361:	EVVAPLMRLL FQQVVSILQR SLPGKDERYE VLFLLDEFKH LGKLEAIETA ITTIAGYKGR 
421:	FMFIIQSLSA LSGTYDEAGK QNFLSNTGVQ VFMATADDET PTYISKAIGE YTFQARSTSY 
481:	SQARMFDHNI QISDQGAPLL RPEQVRLLDD KSEIVLIKGQ PPLKLRKVRY YSDRMLRRLF 
541:	ECQIGALPEP ASLMLAQDVH QDGQDHLSQQ AAVTAALGLG DIDSLVNNGE TPTQQNSDMN 
601:	DEQDNLAIGI YAPQVSVEID DVVEDANARG VAPVSSVPAE MAPALSAQQQ LLGQIIALQQ 
661:	RYRPVSSNPI E