2.A.6.1.2
Heavy metal (Co2+, Zn2+, Cd2+) efflux pump, CzcAB. Functions with CzcC (P13509; 1.B.17.2.2).
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| Accession Number: | P13510 |
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| Protein Name: | Cobalt-zinc-cadmium resistance protein CzcB |
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| Length: | 520 |
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| Molecular Weight: | 54631.00 |
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| Species: | Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) [266264] |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Single-pass membrane protein2 |
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| Substrate |
cadmium(2+), cobalt(2+), zinc(2+) |
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1: MAISNKQKAA IAAIVLVGGV ATGGVLLSGR SAPEEQGGHS ESKGHGDTEH HGKQAAEADH
61: KDDKSHGDGE HHEVKKGPNG GALFSRDGYD VEIGTAESKG EARIRLWVSK SGKAVANGVA
121: ATGQLVRATG ESQALKFVVS GDALESQQPV AEPHVFDVTA NVTLPGSSSP LAVRLSKEEG
181: KIELTADQLA KTGVVVQTAG SAKVQAGVQF PGEIRFNEDK TAHVVPRLAG VVESVPANIG
241: QQVKKGQVLA VIASTGLSDQ RSELLAAQKR LDLARVTYDR EKKLWEQKIS AEQDYLSARN
301: ALQEAQISVQ NAQQKLTAIG ASNSSTALNR YELRAPFDGM IVEKHISLGE AVADNANVFT
361: LSDLSSVWAE FVVSAKDVER VRIGEKASIN SASSDVKADG TVSYVGSLLG EQTRTAKARV
421: TLTNPQMAWR PGLFVTVDVF GADVEVPVAV KTEAVQDVNG ESVVFVAVQG GFVPQPVKVG
481: RTNGKVIEIV EGLKPGARYA AANSFVLKAE LGKSSAEHGH