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Accession Number: | P32011 |
Protein Name: | DrrB |
Length: | 283 |
Molecular Weight: | 30614.00 |
Species: | Streptomyces peucetius [1950] |
Number of TMSs: | 6 |
Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
Substrate | doxorubicin, daunorubicin |
Cross database links:
Pfam: | PF01061 |
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Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0046677
P:response to antibiotic
GO:0006810
P:transport
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References (3)[1] “A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin.” Guilfoile P.G.et.al. 1924314 |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MTTSPGTVES TTPVSGQLRT VLSAGERPAR ATAVSATLTH LWRAMMAFKH FPVQLIDIVL 61: MPLIFLLMFT YLFGGAFADS TEEYLQFYLP GVTVQAVVMM TVYTGTSLNT DIHKGVFDRF 121: RTLPFWQPAT LAGSLLGDVL RYVVALATTV SLGLLLGFRA DGGFLGVVGA MLVLIVFGFS 181: VSWIFAALGV VASEPERVSG TSMIVLYPLL FMSNIFVMPE TMPGWMQAIV DANPMSHAAT 241: ASRELMHGTA GFWDVGLVLC VSAGLVAVFA PLTMRLYRNK NAH