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3.A.1.5.3
Nickel porter. Histidine 416 of NikA is essential for nickel uptake (Cavazza et al., 2011).

Accession Number:P33594
Protein Name:NikE aka B3480
Length:268
Molecular Weight:29722.00
Species:Escherichia coli [83333]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Peripheral membrane protein2
Substrate nickel(2+)

Cross database links:

DIP: DIP-10344N
RefSeq: AP_004312.1    NP_417937.1   
Entrez Gene ID: 947987   
Pfam: PF00005   
BioCyc: EcoCyc:NIKE-MONOMER    ECOL168927:B3480-MONOMER   
KEGG: ecj:JW3445    eco:b3480   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016151 F:nickel ion binding
GO:0015413 F:nickel-transporting ATPase activity
GO:0015675 P:nickel ion transport

References (4)

[1] “The nik operon of Escherichia coli encodes a periplasmic binding-protein-dependent transport system for nickel.”  Navarro C.et.al.   7934931
[2] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTLLNISGLS HHYAHGGFNG KHQHQAVLNN VSLTLKSGET VALLGRSGCG KSTLARLLVG 
61:	LESPAQGNIS WRGEPLAKLN RAQRKAFRRD IQMVFQDSIS AVNPRKTVRE ILREPMRHLL 
121:	SLKKSEQLAR ASEMLKAVDL DDSVLDKRPP QLSGGQLQRV CLARALAVEP KLLILDEAVS 
181:	NLDLVLQAGV IRLLKKLQQQ FGTACLFITH DLRLVERFCQ RVMVMDNGQI VETQVVGEKL 
241:	TFSSDAGRVL QNAVLPAFPV RRRTTEKV