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3.A.6.1.1
Type III protein secretion complex. Assembly of the YscR,S,T,U,V complex occurs independently of other structural components and involves the formation of a YscV oligomer (Diepold et al., 2011). A C-terminal region of Yersinia pestis YscD binds the outer membrane secretin YscC (Ross and Plano, 2011). YopBD-mediated translocation of T3SS cargo, but not YopBD pore formation, leads to activation of host pathways influencing inflammation, cell death, and response to stress (Kwuan et al. 2013).

Accession Number:P40290
Protein Name:YscN
Length:439
Molecular Weight:47783.00
Species:Yersinia enterocolitica [630]
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate protein polypeptide chain

Cross database links:

RefSeq: NP_052401.1   
Entrez Gene ID: 1239132   
Pfam: PF00006    PF02874   

Gene Ontology

GO:0005737 C:cytoplasm
GO:0033178 C:proton-transporting two-sector ATPase compl...
GO:0030257 C:type III protein secretion system complex
GO:0005524 F:ATP binding
GO:0046933 F:hydrogen ion transporting ATP synthase acti...
GO:0046961 F:proton-transporting ATPase activity, rotati...
GO:0015986 P:ATP synthesis coupled proton transport
GO:0009405 P:pathogenesis
GO:0030254 P:protein secretion by the type III secretion...

References (2)

[1] “YscN, the putative energizer of the Yersinia Yop secretion machinery.”  Woestyn S.et.al.   8132449
[2] “The lcrE gene is part of an operon in the lcr region of Yersinia enterocolitica O:3.”  Viitanen A.-M.et.al.   2160939

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MLSLDQIPHH IRHGIVGSRL IQIRGRVTQV TGTLLKAVVP GVRIGELCYL RNPDNSLSLQ 
61:	AEVIGFAQHQ ALLIPLGEMY GISSNTEVSP TGTMHQVGVG EHLLGQVLDG LGQPFDGGHL 
121:	PEPAAWYPVY QDAPAPMSRK LITTPLSLGI RVIDGLLTCG EGQRMGIFAA AGGGKSTLLA 
181:	SLIRSAEVDV TVLALIGERG REVREFIESD LGEEGLRKAV LVVATSDRPS MERAKAGFVA 
241:	TSIAEYFRDQ GKRVLLLMDS VTRFARAQRE IGLAAGEPPT RRGYPPSVFA ALPRLMERAG 
301:	QSSKGSITAL YTVLVEGDDM TEPVADETRS ILDGHIILSR KLAAANHYPA IDVLRSASRV 
361:	MNQIVSKEHK TWAGDLRRLL AKYEEVELLL QIGEYQKGQD KEADQAIERI GAIRGWLCQG 
421:	THELSHFNET LNLLETLTQ