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| Accession Number: | P60686 |
| Protein Name: | Na(+)/H(+) antiporter subunit D aka mnhD |
| Length: | 498 |
| Molecular Weight: | 54756.00 |
| Species: | Staphylococcus aureus [1280] |
| Number of TMSs: | 14 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), hydron |
Cross database links:
| Pfam: | PF00361 |
|---|---|
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0008137
F:NADH dehydrogenase (ubiquinone) activity
GO:0015386
F:potassium:hydrogen antiporter activity
GO:0042773
P:ATP synthesis coupled electron transport
GO:0015992
P:proton transport
GO:0006814
P:sodium ion transport
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References (2)[1] “A putative multisubunit Na+/H+ antiporter from Staphylococcus aureus.” Hiramatsu T.et.al. 9852009 [2] “Catalytic properties of Staphylococcus aureus and Bacillus members of the secondary cation/proton antiporter-3 (Mrp) family are revealed by an optimized assay in an Escherichia coli host.” Swartz T.H.et.al. 17293423
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MIESNMLVLT LVIPVITAIL LVFIGKRPII KRYVALGGTL LTLVAAIINL ANVVKHGPIR 61: VELGSWKAPY SIVFVLDIFS ALLIITSIII TAIVILYSYQ TIGIERERYY YYFSVLFMLI 121: GIIGAFTTGD IFNLFVFFEV FLMSSYFLLV IGSTKIQLQE TIKYVLVNVV SSSFFVMGVA 181: ILYSVVGTLN LADISNKLAN LSAHDSGLVN IVFILFIFVF ATKAGVFPMF VWLPSAYYAP 241: PIPIIAFFGA LLTKVGVYAI ARTLSLFFSD NVSFSHYVIL FLALLTIIFG CVGAVAYANI 301: KKIILYNVMI AVGVILVGVA MMTESGMIGA IYYTLHDMLV KLALFLLIGI MIKITGTADL 361: RQFGGLIKRY PVLGWSFFIA ALSLAGIPPL SGFYGKFFIV QSTFERGFYL SGVIVLLSSL 421: VVLYSVIRIF LQGFFGQPKG YDLNNKVDVK YLTTIAIVAV VITVLYGLSA DYLYPMVKAG 481: AETFYNPSTY VKAVLGGK