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3.A.1.5.26 The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).
Accession Number:	P63395
Protein Name:	Uncharacterized ABC transporter ATP-binding protein Rv1281c/MT1318
Length:	612
Molecular Weight:	65293.00
Species:	Mycobacterium tuberculosis [1773]
Substrate	glutathione, bradykinin

Entrez Gene ID:	886997 924755
Pfam:	PF00005 PF08352
KEGG:	mtc:MT1318 mtu:Rv1281c
Gene Ontology GO:0005886 C:plasma membrane GO:0005524 F:ATP binding GO:0016887 F:ATPase activity GO:0015197 F:peptide transporter activity
References (2) [1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.” Cole S.T.et.al. 9634230 [2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.” Fleischmann R.D.et.al. 12218036

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MSPLLEVTDL AVTFRTDGDP VTAVRGISYR VEPGEVVAMV GESGSGKSAA AMAVVGLLPE 
61:	YAQVRGSVRL QGTELLGLAD NAMSRFRGKA IGTVFQDPMS ALTPVYTVGD QIAEAIEVHQ 
121:	PRVGKKAARR RAVELLDLVG ISQPQRRSRA FPHELSGGER QRVVIAIAIA NDPDLLICDE 
181:	PTTALDVTVQ AQILDVLKAA RDVTGAGVLI ITHDLGVVAE FADRALVMYA GRVVESAGVN 
241:	DLYRDRRMPY TVGLLGSVPR LDAAQGTRLV PIPGAPPSLA GLAPGCPFAP RCPLVIDECL 
301:	TAEPELLDVA TDHRAACIRT ELVTGRSAAD IYRVKTEARP AALGDASVVV RVRHLVKTYR 
361:	LAKGVVLRRA IGEVRAVDGI SLELRQGRTL GIVGESGSGK STTLHEILEL AAPQSGSIEV 
421:	LGTDVATLGT AERRSLRRDI QVVFQDPVAS LDPRLPVFDL IAEPLQANGF GKNETHARVA 
481:	ELLDIVGLRH GDASRYPAEF SGGQKQRIGI ARALALQPKI LALDEPVSAL DVSIQAGIIN 
541:	LLLDLQEQFG LSYLFVSHDL SVVKHLAHQV AVMLAGTVVE QGDSEEVFGN PKHEYTRRLL 
601:	GAVPQPDPAR RG

3.A.1.5.26
The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).

Cross database links:

Gene Ontology

References (2)

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3.A.1.5.26The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

3.A.1.5.26
The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).