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3.A.1.5.26 The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).
Accession Number:	P66964
Protein Name:	Putative peptide transport permease protein Rv1282c/MT1319
Length:	291
Molecular Weight:	31374.00
Species:	Mycobacterium tuberculosis [1773]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	glutathione, bradykinin

Entrez Gene ID:	886980 924753
Pfam:	PF00528
KEGG:	mtc:MT1319 mtu:Rv1282c
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0005215 F:transporter activity GO:0015833 P:peptide transport GO:0015031 P:protein transport
References (2) [1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.” Cole S.T.et.al. 9634230 [2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.” Fleischmann R.D.et.al. 12218036

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTEFASRRTL VVRRFLRNRA AVASLAALLL LFVSAYALPP LLPYSYDDLD FNALLQPPGT 
61:	KHWLGTNALG QDLLAQTLRG MQKSMLIGVC VAVISTGIAA TVGAISGYFG GWRDRTLMWV 
121:	VDLLLVVPSF ILIAIVTPRT KNSANIMFLV LLLAGFGWMI SSRMVRGMTM SLREREFIRA 
181:	ARYMGVSSRR IIVGHVVPNV ASILIIDAAL NVAAAILAET GLSFLGFGIQ PPDVSLGTLI 
241:	ADGTASATAF PWVFLFPASI LVLILVCANL TGDGLRDALD PASRSLRRGV R

3.A.1.5.26
The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

3.A.1.5.26The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

3.A.1.5.26
The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis (Dasgupta et al., 2010).