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3.D.4.7.1
Cytochrome oxidase (Cox1-3)

Accession Number:P68530
Protein Name:Cox2 aka MTCO2 aka COII
Length:227
Molecular Weight:26021.00
Species:Bos taurus (Bovine) [9913]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate hydron

Cross database links:

RefSeq: YP_209208.1   
Entrez Gene ID: 3283880   
Pfam: PF00116    PF02790   
KEGG: bta:3283880   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005743 C:mitochondrial inner membrane
GO:0070469 C:respiratory chain
GO:0005507 F:copper ion binding
GO:0004129 F:cytochrome-c oxidase activity
GO:0009055 F:electron carrier activity
GO:0020037 F:heme binding
GO:0022904 P:respiratory electron transport chain
GO:0006810 P:transport

References (6)

[1] “Studies on cytochrome c oxidase, IV[1-3]. Primary structure and function of subunit II.”  Steffens G.J.et.al.   220175
[2] “Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome.”  Anderson S.et.al.   7120390
[3] “The genetic code in bovine mitochondria: sequence of genes for the cytochrome oxidase subunit II and two tRNAs.”  Young I.G.et.al.   6265319
[4] “The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A.”  Tsukihara T.et.al.   8638158
[5] “Structure analysis of bovine heart cytochrome c oxidase at 2.8 A resolution.”  Tomizaki T.et.al.   10089392
[6] “X-ray structure of azide-bound fully oxidized cytochrome c oxidase from bovine heart at 2.9 A resolution.”  Fei M.J.et.al.   10771420
Structure:
1OCC   1OCO   1OCR   1OCZ   1V54   1V55   2DYR   2DYS   2EIJ   2EIK   [...more]

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAYPMQLGFQ DATSPIMEEL LHFHDHTLMI VFLISSLVLY IISLMLTTKL THTSTMDAQE 
61:	VETIWTILPA IILILIALPS LRILYMMDEI NNPSLTVKTM GHQWYWSYEY TDYEDLSFDS 
121:	YMIPTSELKP GELRLLEVDN RVVLPMEMTI RMLVSSEDVL HSWAVPSLGL KTDAIPGRLN 
181:	QTTLMSSRPG LYYGQCSEIC GSNHSFMPIV LELVPLKYFE KWSASML