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3.A.1.122.18
MacAB-TolC MDR effllux porter. Exports macrolide antibiotics, virulence factors, peptides and cell envelope precursors. The 3-d crystal structure of MacB has been solved at 3.4 Å resolution (Okada et al. 2017). MacB forms a dimer in which each protomer contains a nucleotide-binding domain and four TMSs that protrude in the periplasm into a binding domain for interaction with the membrane fusion protein MacA. It has unique structural features (Okada et al. 2017).

Accession Number:Q2FD52
Protein Name:Efflux transporter, RND family, MFP subunit
Length:445
Molecular Weight:48145.00
Species:Acinetobacter baumannii [470]
Number of TMSs:1
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPKIKPIKLV IIVVCIAIIA VLAWKFLKPK QQQPQYITAE VTRGDIENNV LATGTLDATK 
61:	LISVGAQVSG QVKKMYVQLG DQVKQGQLIA QIDSTTQENS LKTSDANIKN LEAQRLQQIA 
121:	SLNEKQLEYR RQQQMYAQDA TPRADLESAE AAYKTAQAQV KALDAQIESA KITRSTAQTN 
181:	IGYTRIVAPT DGTVVAIVTE EGQTVNANQS APTIVKIAKL QNMTIKAQVS EADIMKVEKG 
241:	QQVYFTTLGD ETKRYATLRQ IEPAPDSISS ESNSTTSSTT SSAVYYNALF DVPNTDGKLR 
301:	IDMTAQVYIV LNSAKNALLV PSSALSSKQF SGQRKQGQSA DKASSTPSAE RKHQGNGVRL 
361:	ERLNLTPEQK QLIEQGKATL SVVRVLQADG TTKPTQILVG INNRVNAQVL AGLKQGDQVV 
421:	IADSSENSAA SANSGNNRRR GPMGM