3.A.1.20.5
A Mg2+-citrate uptake porter with three components, R, M and C, as suggested by Mandal et al. 2019. This system alao be a ferric iron uptake system, based on sequence similarity studies (see other members of TC sub-family 3.A.1.20). The substrate binding protein, MctA, of the system, has been studied with and without Mg-citrate, and the 3-D structure at up to 1.63 Å resolution, indicating that this comopound is a true substrate of the system (Mandal and Kanaujia 2021).
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| Accession Number: | Q53VZ2 |
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| Protein Name: | Iron ABC transporter, periplasmic iron-binding protein |
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| Length: | 358 |
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| Molecular Weight: | 39861.00 |
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| Species: | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [300852] |
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| Substrate |
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1: MRRAILWFVA LAIASVLAQQ SRPASDPQVV EAARKEGRLI IYSSTDQSSA QALLDDFRKL
61: YPFIQIEYND LGTQAIYDRF VSETAAGASS ADLLWSSAME LQVKLASEGY ALPYDSPEAK
121: NWPANARLGN LAYSTTLEPA VVVYNKRFLK PEEVPTTREG LARLLQEPRM RGRVATWDPE
181: RSAVGFTILK ADYDRFPAFQ ELARAFGKAQ AALYSSTGAA FEKVISGEHY LAYGFFGSYA
241: LLRQRTVKDL GIAYLTDGTV AIQRVAFINK RAAHPNAAKL FLDYLLSLRG QNLMAYTALI
301: FARRETVVGE ATPQALYKAV GGKDKVYAIP VSTEILKNLD PAERMRFLTF WRQAVRGQ