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3.A.1.14.5 Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).
Accession Number:	Q56991
Protein Name:	HmuT aka YPO0281 aka Y0541
Length:	279
Molecular Weight:	29574.00
Species:	Yersinia pestis [632]
Location¹ / Topology² / Orientation³:	Periplasm¹
Substrate	ferroheme b

Structure:
RefSeq:	NP_667878.1 NP_991830.1 YP_002345363.1
Entrez Gene ID:	1145488 1173127 2766946
Pfam:	PF01497
BioCyc:	YPES187410:Y0541-MONOMER YPES214092:YPO0281-MONOMER YPES229193:YP0436-MONOMER
KEGG:	ype:YPO0281 ypk:y0541 ypm:YP_0436
Gene Ontology GO:0042597 C:periplasmic space GO:0005381 F:iron ion transmembrane transporter activity GO:0006827 P:high-affinity iron ion transport
References (4) [1] “The hmu locus of Yersinia pestis is essential for utilization of free haemin and haem-protein complexes as iron sources.” Hornung J.M.et.al. 9026634 [2] “Genome sequence of Yersinia pestis, the causative agent of plague.” Parkhill J.et.al. 11586360 [3] “Genome sequence of Yersinia pestis KIM.” Deng W.et.al. 12142430 [4] “Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.” Song Y.et.al. 15368893
3MD9

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MRLRLLSLPF ILSLCAPLLP LNTLAAERIV TIGGDVTEIA YALGAGDEIV ARDSTSQQPQ 
61:	AAQKLPDVGY MRTLNAEGIL AMKPTMLLVS ELAQPSLVLT QIASSGVNVV TVPGQTTPES 
121:	VAMKINAVAT ALHQTEKGQK LIEDYQQRLA AVNKTPLPVK VLFVMSHGGL TPMAAGQNTA 
181:	ADAMIRAAGG SNAMQGFSRY RPLSQEGVIA SAPDLLLITT DGVKALGSSE NIWKLPGMAL 
241:	TPAGKHKRLL VVDDMALLGF GLETPQVLAQ LREKMEQMQ

3.A.1.14.5
Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

3.A.1.14.5Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

3.A.1.14.5
Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).