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2.A.6.2.4
The multidrug resistance pump, AdeDE (exports amikacin, ceftazidime, chloramphenicol, ciprofloxacin, erythromycin, ethidium bromide, meropenem, rifampin, and tetracycline) (Chau et al., 2004).

Accession Number:Q67GM1
Protein Name:AdeD
Length:374
Molecular Weight:40598.00
Species:Acinetobacter sp. 4365 [209657]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate rifampicin, ciprofloxacin, chloramphenicol, tetracycline, erythromycin A, ethidium bromide, amikacin, ceftazidime, meropenem

Cross database links:

Pfam: PF00529   

Gene Ontology

GO:0016020 C:membrane
GO:0008565 F:protein transporter activity
GO:0009306 P:protein secretion

References (1)

[1] “Novel resistance-nodulation-cell division efflux system AdeDE in Acinetobacter genomic DNA group 3.”  Chau S.L.et.al.   15388479

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MFGSVFFNHK YLWLLPLLLF LNGCDSDPPA PKNIQQVGTI TIKPETIESN YQLAGRTVAS 
61:	EISQVRPQVN GVVIEQLFKE GTQVNKGQPL YKIDSSLYRD SVDEAAGNLA LAKATVNSTR 
121:	LQAERYKELI KVNGVSQQEL DNAQSAYEQA KATVAVNEAV LKTARTNLRY TQVSAPISGR 
181:	IGRSSITRGA LVTSAQTDPL ATIQKLDPMY VDLTQSSDEY MALRKQLTEN GIKPTELSVR 
241:	LKLENGTNYA EQGTFKFSDV AVDEATGSVT LRAAFPNPNN ALLPGLYVRA ELGTGTRPNS 
301:	VLIPQGALFR DAEGNPLVWI VGKDNKAEQR KITLGSAIDN RWLVTSGLKA GDQVIVDGLQ 
361:	GLSAGMTIEP TPMS