3.D.1.5.1
Proton-translocating NADH dehydrogenase I. NDUFS4 is an accessory subunit of the mitochondrial membrane respiratory chain NADH
dehydrogenase (Complex I), that is believed not to be involved in
catalysis. However, a knockout of NDUFS4 in human iPSCs provides a model for mitochondrial complex I deficiencyin humans (Goolab et al. 2025).
|
| Accession Number: | Q746T6 |
|---|
| Protein Name: | NADH-quinone oxidoreductase subunit K 2 |
|---|
| Length: | 102 |
|---|
| Molecular Weight: | 11189.00 |
|---|
| Species: | Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) [243231] |
|---|
| Number of TMSs: | 3 |
|---|
| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
hydron |
|---|
1: MIVPFEHVLI LAGLLFALGL VCVLVWRMNL IMLLIGIEVM LNAAMLAFVG GAARWGMADG
61: QVFSLIIMAL TSAEVSLALA MVVYLHRRKK TVDADEFREL QG