3.A.2.2.10
13 component V-type ATPase of Plasmodium falciparum. (1) VapA (V1 subunit A; 611 aas), (2) VapB (V1 subunit B; 494 aas), (3) VapC (V1 subunit C; 383 aas), (4) V1 subunit D; 347 aas), (5) VapE (V1 subunit E; 235 aas), (6) VapF (V1 subunit F; 128 aas), (7) VapG (V1 subunit G; 123 aas) (8) VapH; V1 subunit; 455 aas), (9) Vo subunit a; 299 aas), (10) Vo subunit c; 165 aas), (11) Vo subunit C*; 181 aas), (12) Vo subunit d; 382 aas), (13) Vo subunit e; 78 aas). The system is involved in the active export of H+ from the cytoplasm (Wunderlich 2022).
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| Accession Number: | Q76NM6 |
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| Protein Name: | V-type proton ATPase catalytic subunit A |
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| Length: | 611 |
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| Molecular Weight: | 68576.00 |
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| Species: | Plasmodium falciparum (isolate 3D7) [36329] |
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| Substrate |
hydron |
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1: MTKVAVEKEE PGVVYKVAGS LVIAENMSGT RMYELAKVGW NKLVGEIIRL EGNYAYIQVY
61: EDTSGLSVGD PVIKTGNALS VELGPGILDN IYDGIQRPLE RIANVCGDVY IYKGIDMTSL
121: DHDKQWQFYA DKKLKLNDIV TGGDIFGFVD ENKLFKEHKI MAPPNAKGRL TYIAPDGSYT
181: LKDKIFELEY QGKKYTYGLS HLWPVRDPRP VLEKVTGDTL LLTGQRVLDS LFPTVQGGTC
241: AIPGAFGCGK TCVSQALSKY SNSEVIIYVG CGERGNEMAE ILSDFPELTT KVDNEDVGIM
301: QRTCLVANTS NMPVAAREAS IYTGITLCEY FRDMGYNATM MADSTSRWAE ALREISGRLA
361: EMPADSGYPA YLGARLASFY ERAGKVKCIG SPSRIGSITI VGAVSPPGGD FSDPVTTATM
421: SIVQAFWGLD KKLAQRKHFP SVNWSTSFSK YVRQLEQYFD NFDQDFLSLR QKISDILQQE
481: SDLNDIVQLV GKDSLSEDQK VVMEVAKIIR EDFLQQNAFS DYDYMCPLQK TVGMMRIICH
541: FYAQCLRTLQ EYDSRERKIG WGSIYNTLRP TINKITHMKF ENPKNSDEYF KKYFKALEEE
601: ITVGLRNLME K