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2.A.6.2.19
The multidrug efflux pump, EefABC (exports chloramphenicol, ciprofloxacin, erythromycin, tetracycline and doxycycline) (Masi et al., 2005). EefC exhibits low ionic selectivity (Masi et al., 2007).

Accession Number:Q8GC84
Protein Name:EefA lipoprotein precursor
Length:374
Molecular Weight:39375.00
Species:Enterobacter aerogenes (Aerobacter aerogenes) [548]
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ion, ciprofloxacin, chloramphenicol, tetracycline, doxycycline, erythromycin A

Cross database links:

Pfam: PF00529   

Gene Ontology

GO:0016020 C:membrane
GO:0008565 F:protein transporter activity
GO:0009306 P:protein secretion

References (1)

[1] “The eefABC multidrug efflux pump operon is repressed by H-NS in Enterobacter aerogenes.”  Masi M.et.al.   15901719

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MKHIIAPIAT ALFLLSGCDN VQTTAPQQPT PEVGIVTLQA QPVPVVSQLT GRTTASLSAE 
61:	VRPQVGGIIQ KRLFTEGDMV KAGQALYQID PSSYRATWNE AAAALKQAQA LVVSDCQKAQ 
121:	RYASLVRDNG VSRQDADDAA SACAQDKASV ESKKAALESA RINLNWTTVT APIAGRIGIS 
181:	SVTPGALVSA DQDTALATIR GLDTMYVDLT RSSVDLLRLR RQSLASNSDT LSVTLTLEDG 
241:	STYPEKGRLA LTEVAVDEST GSVTLRAIFP NPQHVLLPGM FVRARIDEGI MNDAILAPQQ 
301:	GITRDAKGDA TALVVDADNN VEQRTVQTGD TYGDKWLVLS GLKAGDKLIV EGTGKVSPGQ 
361:	AVKAVAVKNN GGNA