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3.A.7.8.1
Competence system for DNA uptake (ComB) (Hofreuter et al., 2003; Karnholz et al., 2006). DNA uptake into the periplasm occurs preferentially at the poles. Transport into the cytoplasm depends on ComEC. Thus, DNA uptake may occur in a two step process (Stingl et al., 2010).

Accession Number:Q8RMY8
Protein Name:VirB8 aka ComB8
Length:352
Molecular Weight:40992.00
Species:Helicobacter pylori (Campylobacter pylori) [210]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate DNA

Cross database links:

Pfam: PF04335   

References (2)

[1] “Cluster of type IV secretion genes in Helicobacter pylori's plasticity zone.”  Kersulyte D.et.al.   12813069
[2] “Microevolution of Helicobacter pylori type IV secretion systems in an ulcer disease patient over a ten-year period.”  Alvi A.et.al.   17942650

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSNLQELREH LKELENSFEI GSFTKENIKE YAKCFFMSLS MFLEEQEKNQ QEEFLEQDTK 
61:	ENQEELIKSI QTSIAKNQEL EKISFEKWEN KIQERVLPKL KRIVTHKLQE SITSSINTQL 
121:	ESFKKDELDL SSVFEIQRKN TQIAYRLAIG GLIGIIALSI AIFIMMPLKE NTPYFIDFAN 
181:	SDKHFAVVQR ADTKVDYSEA FLRNLVGSYI TARETINHID DKIRLNETIR EQSSEEVWKT 
241:	LEQLVSGKGS IYSNSNMDRE IKIINISIYK QGKQQNIAVA DIVAKVFDKG YLICEKRDRV 
301:	SLIYHFKPLI QFDYSSMPKN PTGFIVDKYS LSEIASIKAL DKTYKKVERT PF