TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.4.3
General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC.

Accession Number:Q8VM85
Protein Name:BraD aka Bra2D
Length:290
Molecular Weight:30764.00
Species:Rhizobium leguminosarum (biovar viciae) [387]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate alpha-amino acid, gamma-aminobutyric acid

Cross database links:

Pfam: PF02653   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Rhizobium leguminosarum has a second general amino acid permease with unusually broad substrate specificity and high similarity to branched-chain amino acid transporters (Bra/LIV) of the ABC family.”  Hosie A.H.et.al.   12107123

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MLSTILEQSV NGIVTGSVYA IVAVGMTMIF GVLRAINFAH GEYYMLGTFG AWFAIDYLGL 
61:	SYEVSIVVGV LATIAVAYVV GQLVMRRMVG APAESGVLAT LGIALILQNT IILVFGGGYK 
121:	FFAGGYIEPV SILGFSLAEQ RILILVVCLL VFIGLELMVS YTRLGMAMRA VSQNVECCSV 
181:	VGIDVPQVVL RTFMLGAALA ALSGVLTAPV NVSVYGGMGE LITFKTLPII IMGGLGNVRG 
241:	TFVAAMILGV AESLVATYVG LQFRDTGSFA TLILMLMWRP HGLFSTQARF