3.A.1.4.12
ABC-type uptake porter for pyruvate and monocarboxylate 2-oxo acids. Pyruvate uptake has been measured and is inhibited by monocarboxylate 2-oxo-acids such as 2-oxobutyrate, 2-oxovalerate, 2-oxoisovalerate, 2-oxoisocaproate and 2-oxo 3-methylvalerate which are probably substrates (Pernil et al. 2010).
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| Accession Number: | Q8YU22 |
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| Protein Name: | ATP-binding protein of branched-chain amino acid ABC transporter |
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| Length: | 259 |
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| Molecular Weight: | 28621.00 |
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| Species: | Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) [103690] |
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| Number of TMSs: | 3 |
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| Substrate |
3-methyl-2-oxovalerate, 2-oxopentanoate, pyruvate, 2-oxobutanoate |
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1: MSLDKSRVIL EAKSLTRRFG GLVAVNNVSF TVNHYEIFGL IGPNGAGKTT LFNLITALIP
61: PSSGELIYQN KAIAKLRPHQ IASLGIARTF QNIRLFGELS ALENVIIARH LHTKSTIFTG
121: VLGLPPAPKE ESRSREKALE LLEMVGLSDR AQEKARNFAY GDQRRLEIAR ALALEPQILL
181: LDEPAAGMNP SEKQQLSDFI REIRDRFNLT IILIEHHVPL VMGLCDRIAV LDFGQLIALG
241: EPSVVRNDPA VIEAYLGNE