3.A.1.4.12
ABC-type uptake porter for pyruvate and monocarboxylate 2-oxo acids. Pyruvate uptake has been measured and is inhibited by monocarboxylate 2-oxo-acids such as 2-oxobutyrate, 2-oxovalerate, 2-oxoisovalerate, 2-oxoisocaproate and 2-oxo 3-methylvalerate which are probably substrates (Pernil et al. 2010).
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| Accession Number: | Q8YU23 |
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| Protein Name: | Permease protein of branched-chain amino acid ABC transporter |
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| Length: | 308 |
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| Molecular Weight: | 33063.00 |
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| Species: | Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) [103690] |
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| Number of TMSs: | 8 |
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| Substrate |
3-methyl-2-oxovalerate, 2-oxopentanoate, pyruvate, 2-oxobutanoate |
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1: MAEFFSTYGS LIVSMVLGAL LGLSLYLPLM AGQLSLASPG FYALGGYIAA ILSTKVFQTN
61: SNSFPIPLLL LEMLIAAVVS GLLGIAVGIP ALRLRGIYLA IATIAFVEVL RVLSLNLDIT
121: GGAVGIFGIP QPFQTPIEYL WITLPLLLIS MVLFYRLERV RVGRAFTAIR EDELAAGAMG
181: INPTYYKVLA FTLGAMLAGI VGVISAHFLN TWNARQGTFD ASIIYLTFVL IGGSRTFLGS
241: VVGGMVFTAL PEVLRGLADT GGFPTWLAQF LRDGRLIIFG LLIVTGTIFF PQGLVTPDIF
301: KFGKPKNR